144340-82-9

Upstream product

• 2220-40-8 bicyclo[2.2.2]oct-5-en-2-one 
• 51173-82-1 3-Methyl-bicyclo<2.2.2>oct-5-en-2-on 
• 144340-80-7 (3R*)-3-Methyl-3-<2-(1,3-dioxolan-2-yl)>-ethyl-bicyclo<2.2.2>oct-5-en-2-on 
• 144340-81-8 3-Methyl-3-<2-(1,3-dioxolan-2-yl)>-ethyl-bicyclo<2.2.2>octan-2-on 
• 18742-02-4 2-bromo-2-(2-ethyl)dioxolane 
• 144340-89-6 2,3-Dimethyl-3-<2-(1,3-dioxolan-2-yl)>-ethyl-bicyclo<2.2.2>octan-2-ol 

Relevant academic research and scientific papers

Synthesis and Odour of (Z)-Dehydro-homo-β-santalol

Guided by molecular modeling studies, the synthesis of the title compound is described.The organoleptic evaluation proved the predicted real sandal like odour of (Z)-dehydro-homo-β-santalol. - Keywords: Bicyclooctane derivatives; Computer aided fragrance design; Molecular modeling; Sandalwood odorants; Structure-odour-relationship

Synthese und Geruch von Tricyclo2,7>dodecan-Derivaten

The acetale-ketone 9 was synthesized as precursor for the preparation of β-santalol derivatives possessing a bicyclooctane nucleus.After methylenation of the keto-group the subsequent acidic hydrolysis of the acetal leads via a Prins reaction of the liberated aldehyde with the methylene group to tricyclo2,7>dodecane derivatives.Their olfactory properties are described. Keywords.Bicyclooctane derivatives; Tricyclo2,7>dodecane derivatives; α-Alkylation; Prins reaction; Flavour