1443523-28-1

Basic information

• Product Name: (Z)-N-(2-(4-chlorophenyl)-3-cyclopropyl-4H-pyrido[1,2-a]pyrimidin-4-ylidene)-4-methylbenzenesulfonamide
• Synonyms: (Z)-N-(2-(4-chlorophenyl)-3-cyclopropyl-4H-pyrido[1,2-a]pyrimidin-4-ylidene)-4-methylbenzenesulfonamide
• CAS NO: 1443523-28-1
• Molecular Weight: 449.961
• Mol File: 1443523-28-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-N-(2-(4-chlorophenyl)-3-cyclopropyl-4H-pyrido[1,2-a]pyrimidin-4-ylidene)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-N-(2-(4-chlorophenyl)-3-cyclopropyl-4H-pyrido[1,2-a]pyrimidin-4-ylidene)-4-methylbenzenesulfonamide(1443523-28-1)
• EPA Substance Registry System: (Z)-N-(2-(4-chlorophenyl)-3-cyclopropyl-4H-pyrido[1,2-a]pyrimidin-4-ylidene)-4-methylbenzenesulfonamide(1443523-28-1)

Safety Data

• Hazardous Substances Data: 1443523-28-1(Hazardous Substances Data)

Upstream product

• 941-55-9 4-toluenesulfonyl azide 
• 59045-98-6 2-<(p-chlorobenzylidene)amino>pyridine 
• 6746-94-7 Cyclopropylacetylene 
• 504-29-0 2-aminopyridine 
• 104-88-1 4-chlorobenzaldehyde 

Relevant articles and documents

Copper(I)-catalyzed [3+2] cycloaddition/ring-opening rearrangement/[4+2] cycloaddition/aromatization cascade: An unprecedented chemo- and stereoselective three component coupling of sulfonyl azide, alkyne and N-arylidenepyridin-2- amine to pyrido[1,2-a]pyrimidin-4-imine

A novel synthetic protocol for the one-pot chemo- and stereoselective construction of diversely functionalized pyrido[1,2-a]pyrimidin-4-imines via copper(I)-catalyzed [3+2] cycloaddition/ring-opening rearrangement/[4+2] cycloaddition/aromatization cascade of sulfonyl azides, alkynes and N-arylidenepyridin-2-amines under mild reaction conditions is reported. In addition, the catalytic activity of copper(I)-modified zeolite, a recyclable, heterogeneous catalyst is also investigated, which gives improved yield compared to its homogeneous equivalents. Copyright