1443529-53-0Relevant academic research and scientific papers
Amino acid-derived phosphonium salts-catalyzed michael addition of 3-substituted oxindoles
Wu, Xiaoyu,Liu, Qin,Liu, Yong,Wang, Qun,Zhang, Ying,Chen, Jie,Cao, Weiguo,Zhao, Gang
, p. 2701 - 2706 (2013/10/21)
A new type of phosphonium phase-transfer catalyst prepared from easily available chiral amino acids was evaluated in a model reaction between oxindole and methyl vinyl ketone, and the catalyst derived from isoleucine was found to be the best. Michael additions of 3-monosubstituted oxindoles to methyl vinyl ketone, acrolein or propargyl aldehyde proceeded smoothly to afford 3,3-disubstituted oxindoles in good to excellent yields with moderate to excellent ees. Copyright
Thiourea-phosphonium salts from amino acids: Cooperative phase-transfer catalysts in the enantioselective aza-Henry reaction
Cao, Dongdong,Chai, Zhuo,Zhang, Jiaxing,Ye, Zhengqing,Xiao, Hua,Wang, Hongyu,Chen, Jinhao,Wu, Xiaoyu,Zhao, Gang
supporting information, p. 5972 - 5974 (2013/07/11)
New chiral bifunctional thiourea-phosphonium salts have been developed based on natural amino acids as highly efficient phase-transfer catalysts in the enantioselective aza-Henry reaction.
