144357-56-2

Upstream product

• 144357-48-2 4,4,7,7-tetramethyl-2-(3-phenylpropyloxy)-1,3,2-dioxaphospholane 
• 100-51-6 benzyl alcohol 
• 122-97-4 3-Phenyl-1-propanol 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 145072-70-4 2-diethylamino-4,4,5,5-tetramethyl-1,3,2-dioxaphospholane 

Relevant academic research and scientific papers

Some properties of cyclic phosphoramidites and their phosphites: Phosphitylation, ester exchange, and hydrolysis

Phosphorylation of diols using sterically bulky cyclic phosphoramidites was performed in a good selectivity. Their phosphite derivatives underwent tetrazole-catalyzed hydrolysis and transesterification. The reaction was shown to proceed via a phosphorane intermediate by NMR analysis.

1H-Tetrazole Catalysed Reactions of Trialkyl Phosphites: Observation of a Five-membered Cyclic Hydrophosphorane Intermediate during the Transesterification

1H-Tetrazole-catalysed transesterification of a trialkyl phosphite with an alcohol and a (31)P NMR experiment in the case of 4,4,5,5-tetramethyl-2-(3-phenylpropoxy)-1,3,2-dioxaphospholane showed the existence of the corresponding cyclic five-coordinate hydrophosphorane as an intermediate.