144367-93-1Relevant academic research and scientific papers
Intramolecular asymmetric heck reactions: Evidence for dynamic kinetic resolution effects
McDermott, Michael C.,Stephenson, G. Richard,Hughes, David L.,Walkington, Andrew J.
, p. 2917 - 2920 (2006)
Enantioselectivity of the cyclization of 1 varies at different stages in the reaction. X-ray crystallography has shown that 1 exists as enantiomerically pure (M) and (P) chiral helical structures defined by the relative orientations of the arene, amide, a
Cobalt-mediated aryl radical cyclisations: A formal synthesis of physovenine
Clark, Andrew J.,Jones, Keith
, p. 6875 - 6882 (2007/10/02)
A synthesis of the tetrahydrofuro[2,3-b]indole (3) in 6 steps from 4-methoxyaniline involving a key cobalt-mediated radical cyclisation is presented. This heterocycle is a known, late intermediate in the synthesis of the alkaloid physovenine (2).
