144370-33-2

Basic information

• Product Name: 2-Pentanone, 4-hydroxy-3-methylene-, (S)- (9CI)
• Synonyms: 2-Pentanone, 4-hydroxy-3-methylene-, (S)- (9CI)
• CAS NO: 144370-33-2
• Molecular Formula: C₆H₁₀O₂
• Molecular Weight: 114.1424
• Product Categories: ACETYLGROUP
• Mol File: 144370-33-2.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 205.5±23.0 °C(Predicted)
• Appearance: /
• Density: 0.971±0.06 g/cm3(Predicted)
• PKA: 13.53±0.20(Predicted)
• CAS DataBase Reference: 2-Pentanone, 4-hydroxy-3-methylene-, (S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentanone, 4-hydroxy-3-methylene-, (S)- (9CI)(144370-33-2)
• EPA Substance Registry System: 2-Pentanone, 4-hydroxy-3-methylene-, (S)- (9CI)(144370-33-2)

Safety Data

• Hazardous Substances Data: 144370-33-2(Hazardous Substances Data)

Upstream product

• 75-07-0 acetaldehyde 
• 78-94-4 methyl vinyl ketone 
• 2747-53-7 (E)-3-methylpent-3-en-2-ol 
• 4485-08-9 4-nitrosonitrobenzene 
• 74457-16-2 4-hydroxy-3-(phenylthiomethyl)-2-pentanone 
• 74457-17-3 4-Hydroxy-3-methylselanylmethyl-pentan-2-one 

Downstream Products

• 189507-88-8 (E)-3-ethylidene 4-phenylbutan-2-one 
• 1163119-98-9 (E)-3-(3-methoxybenzyl)pent-3-en-2-one 
• 1163119-91-2 (E)-3-(2-methylbenzyl)pent-3-en-2-one 
• 1163119-92-3 (E)-3-(4-fluorobenzyl)pent-3-en-2-one 
• 1163120-20-4 (3E,5E)-3-(ethylidene)-6-phenylhex-5-en-2-one 
• 1163119-94-5 (E)-3-(2,4-dichlorobenzyl)pent-3-en-2-one 
• 1163120-03-3 (E)-3-(4-trifluoromethylbenzyl)pent-3-en-2-one 
• 1163119-96-7 (E)-3-(3-bromobenzyl)pent-3-en-2-one 
• 1163120-00-0 (E)-3-(4-methoxybenzyl)pent-3-en-2-one 
• 1163119-93-4 (E)-3-(3-chlorobenzyl)pent-3-en-2-one 
• 79044-47-6 1-(4-Acetyl-1-vinyl-cyclohex-3-enyl)-ethanone 
• 130973-43-2 syn-3-methylene epoxy-4-hydroxy-pentan-2-one 

Relevant articles and documents

Highly functionalized donor-acceptor cyclopropanes applied toward the synthesis of the Melodinus alkaloids

Abstract A series of highly substituted vinylcyclopropanes were prepared and examined as reaction partners in a palladium-catalyzed (3+2) cycloaddition with nitrostyrenes. Described herein are our efforts to synthesize an elusive 1,1-divinylcyclopropane by several distinct approaches, and to apply surrogates of this fragment toward the synthesis of the Melodinus alkaloids.

Baylis-Hillman reaction under solvent-free conditions - Remarkable rate acceleration and yield enhancement

A simple and efficient method has been developed for remarkable rate acceleration and yield enhancement of the Baylis-Hillman reaction under solvent-free "neat conditions" and solvent-less isolation of products. Reaction of equimolar quantities of aldehyd

Octanol-accelerated Baylis-Hillman reaction

The Baylis-Hillman reaction was greatly accelerated by use of octanol as an additive. Under the octanol-accelerated Baylis-Hillman conditions, unactivated aldehydes such as aliphatic aldehydes and aromatic aldehydes with electron-withdrawing substituents