144373-56-8

Basic information

• Product Name: 5-Oxa-2-azaspiro[3.5]nonane-8-carboxylic acid, 1,6-dioxo-, phenylMethyl ester, (4R,8R)-rel-
• Synonyms: 5-Oxa-2-azaspiro[3.5]nonane-8-carboxylic acid, 1,6-dioxo-, phenylMethyl ester, (4R,8R)-rel-;ZIIFEFCXGIQLOL-XHDPSFHLSA-N
• CAS NO: 144373-56-8
• Molecular Formula: C₁₅H₁₅NO₅
• Molecular Weight: 289.2833
• Mol File: 144373-56-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 577.4°C at 760 mmHg
• Flash Point: 303°C
• Appearance: /
• Density: 1.36g/cm³
• Vapor Pressure: 2.48E-13mmHg at 25°C
• Refractive Index: 1.591
• PKA: 12.84±0.40(Predicted)
• CAS DataBase Reference: 5-Oxa-2-azaspiro[3.5]nonane-8-carboxylic acid, 1,6-dioxo-, phenylMethyl ester, (4R,8R)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Oxa-2-azaspiro[3.5]nonane-8-carboxylic acid, 1,6-dioxo-, phenylMethyl ester, (4R,8R)-rel-(144373-56-8)
• EPA Substance Registry System: 5-Oxa-2-azaspiro[3.5]nonane-8-carboxylic acid, 1,6-dioxo-, phenylMethyl ester, (4R,8R)-rel-(144373-56-8)

Safety Data

• Hazardous Substances Data: 144373-56-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H15NO5/c17-12-6-11(7-15(21-12)9-16-14(15)19)13(18)20-8-10-4-2-1-3-5-10/h1-5,11H,6-9H2,(H,16,19)/t11-,15+/m0/s1

Upstream product

• 144373-54-6 *-trans)>-2-(tert-butyldimethylsilyl)-1,6-dioxo-5-oxa-2-azaspiro<3.5>nonane-8-carboxylic acid benzyl ester 

Downstream Products

• 144373-58-0 *-trans)>-1,6-dioxo-5-oxa-2-azaspiro<3.5>nonane-8-carboxylic acid 

Relevant articles and documents

ATP-citrate lyase as a target for hypolipidemic intervention. Sulfoximine and 3-hydroxy-β-lactam containing analogues of citric acid as potential tight-binding inhibitors

Citric acid analogues (±)-12a,b and (±)-17a,b, where one of the primary carboxylates has been replaced by a sulfoximinoyl and a 3-(3-hydroxy-β- lactamyl) moiety, respectively, have been synthesized and evaluated as inhibitors of ATP-citrate lyase. The des