1443775-53-8Relevant articles and documents
New superacid synthesized (fluorinated) tertiary benzenesulfonamides acting as selective hCA IX inhibitors: Toward a new mode of carbonic anhydrase inhibition by sulfonamides
Metayer, Benoit,Mingot, Agnes,Vullo, Daniella,Supuran, Claudiu. T.,Thibaudeau, Sebastien
, p. 6015 - 6017 (2013/07/27)
Tertiary substituted (fluorinated) benzenesulfonamides were synthesized in superacid HF/SbF5 and tested as inhibitors of human carbonic anhydrases (hCAs, EC 4.2.1.1). Strong selectivity toward tumor-associated hCA IX, without inhibiting the off