1443775-63-0Relevant academic research and scientific papers
Synthesis and evaluation of 18F-labeled tertiary benzenesulfonamides for imaging carbonic anhydrase IX expression in tumours with positron emission tomography
Lau, Joseph,Pan, Jinhe,Zhang, Zhengxing,Hundal-Jabal, Navjit,Liu, Zhibo,Bénard, Fran?ois,Lin, Kuo-Shyan
supporting information, p. 3064 - 3068 (2014/06/24)
Three tertiary benzenesulfonamide inhibitors 4a-c were radiolabeled with 18F and evaluated for imaging carbonic anhydrase IX (CA IX) expression with positron emission tomography. All three inhibitors exhibit 10 nM affinity for CA IX with no me
New superacid synthesized (fluorinated) tertiary benzenesulfonamides acting as selective hCA IX inhibitors: Toward a new mode of carbonic anhydrase inhibition by sulfonamides
Metayer, Benoit,Mingot, Agnes,Vullo, Daniella,Supuran, Claudiu. T.,Thibaudeau, Sebastien
supporting information, p. 6015 - 6017 (2013/07/27)
Tertiary substituted (fluorinated) benzenesulfonamides were synthesized in superacid HF/SbF5 and tested as inhibitors of human carbonic anhydrases (hCAs, EC 4.2.1.1). Strong selectivity toward tumor-associated hCA IX, without inhibiting the off
