144397-19-3

Upstream product

• 144397-07-9 (4R,5S)-2-Chloromethyl-4-methyl-5-phenyl-4,5-dihydro-oxazole 
• 37577-28-9 (1S,2R)-(+)-norphedrine 

Relevant academic research and scientific papers

Preparation of functionalized oxazolines

The preparation of several oxazolines substituted at C-2 by an hetero substituted methyl group is reported. 2-Aminomethyl, 2-azidomethyl, 2-nitromethyl and 2-hydroxymethyl oxazolines were obtained by substitution of the corresponding 2-halogenomethyl oxazolines. On the other hand, 2-benzyloxycarbonylaminomethyl, 2-thiophenylmethyl, 2-selenophenylmethyl oxazolines were prepared by condensation of the appropriate iminoether with a β-aminoalcohol.