144448-68-0

Basic information

• Product Name: Imidazo[1,2-b]pyridazine, 3-methoxy-6-[[(4-methoxyphenyl)methyl]thio]-2-(2-phenylethyl)-
• CAS NO: 144448-68-0
• Molecular Formula: C23H23N3O2S
• Molecular Weight: 405.521
• Mol File: 144448-68-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Imidazo[1,2-b]pyridazine, 3-methoxy-6-[[(4-methoxyphenyl)methyl]thio]-2-(2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-b]pyridazine, 3-methoxy-6-[[(4-methoxyphenyl)methyl]thio]-2-(2-phenylethyl)-(144448-68-0)
• EPA Substance Registry System: Imidazo[1,2-b]pyridazine, 3-methoxy-6-[[(4-methoxyphenyl)methyl]thio]-2-(2-phenylethyl)-(144448-68-0)

Safety Data

• Hazardous Substances Data: 144448-68-0(Hazardous Substances Data)

Upstream product

• 121041-62-1 6-(4'-methoxybenzylthio)pyridazin-3-amine 
• 56485-07-5 phenyl-1,2-butanedione 

Relevant articles and documents

Imidazopyridazines. XIII. Syntheses and Central Nervous System Activities of Some 2-Benzyl(phenethyl, biphenyl-4'-yl, 6'-methylnaphthalen-2'-yl, t-butyl and cyclohexyl)-3-methoxy(acylaminomethyl and dimethylaminomethyl)-6-(variously substituted)imidazopyridazines

6-(Variously substituted)-3-methoxy(unsubstituted, dimethylaminomethyl, acetamidomethyl and benzamidomethyl)-2-benzyl(phenethyl, biphenyl-4'-yl, 6'-methylnaphthalen-2'-yl, t-butyl and cyclohexyl)imidazopyridazines have been prepared and examined for activity in the central nervous system.Of these, 2-benzyl-3-methoxy-6-(3'-methoxybenzylamino)imidazopyridazine (IC50 88 nM) bound most strongly to rat brain membrane.In general, the order of activity for groups at the 2-position was Ph>PhCH2>PhCH2CH2>C6H4Ph-p, 6'-methylnaphthalen-2'-yl, c-C6H11 or But.