144457-01-2

Upstream product

• 106-47-8 4-chloro-aniline 
• 144457-16-9 4-ethoxycarbonyl-5-phenyl-6-methyl-4,5-dihydropyrazin-3(2H)-one 
• 93159-92-3 (2-oxo-1-phenyl-propyl)-malonic acid diethyl ester 

Downstream Products

• 192634-36-9 3-Chloro-6-methyl-5-phenyl-pyridazine-4-carboxylic acid (4-chloro-phenyl)-amide 
• 192633-92-4 6-Methyl-3-oxo-5-phenyl-2,3-dihydro-pyridazine-4-carboxylic acid (4-chloro-phenyl)-amide 

Relevant academic research and scientific papers

Pyridazine N-oxides. II. Synthesis and in vitro antimicrobial evaluation of 3-chloro-4-carbamoyl-5-aryl-6-methyl-pyridazine N-oxides

As a part of a research project on antimicrobial agents, various novel carbamoyl derivatives of pyridazine-N-oxides 7a-j were prepared in moderate to good yields from 3-chloro-4-ethoxycarbonyl 5-aryl-6-methyl-3-pyridazine. All compounds synthesized were i

Synthesis and pharmacological activity of 4-carbamoyl-5-aryl-6-methyl-4,5-dihydropyridazin-3 (2H)-ones

A new series of 4-carbamoyl-5-aryl-6-methyl-4,5-dihydropyridazin-3(2H)-ones have been synthesized and tested for their antiinflammatory and analgesic properties. Amongst the test compounds, only 31 showed antiinflammatory activity, though of shorter durat