144460-75-3Relevant academic research and scientific papers
Stereocontrolled Entry to 2,5-Disubstituted Tetrahydrofurans from Hex-2-enono-δ-lactones under Mild Conditions
Gomez, Ana M.,Valverde, Serafin,Lopez, J. Cristobal
, p. 5105 - 5106 (2007/10/02)
A stereospecific route to highly functionalized 2,5-disubstituted tetrahydrofuran derivatives from readily available 6-O-silylated-hex-2-enono-δ-lactones is reported.The protocol involves an efficient Michael type O-heterocyclization reaction followed by selective ring opening of the lactone moiety.
