1444746-89-7Relevant academic research and scientific papers
Insertion of arynes into N-halo bonds: A direct approach to O -haloaminoarenes
Hendrick, Charles E.,McDonald, Stacey L.,Wang, Qiu
, p. 3444 - 3447 (2013/07/26)
A new approach to access o-haloaminoarenes has been achieved by insertion of arynes into a nitrogen-halide bond (N-X). This transition-metal-free transformation displays a broad substrate scope of arynes, good compatibility with functional groups, and high regioselectivity. Representative transformations of the o-haloaminoarenes are described to highlight their utility for rapid access to diversely functionalized aminoarene derivatives.
