1444746-97-7 Usage
Chemical compound
4-(2-bromo-6-methoxyphenyl)morpholine
Class
Morpholines
Structure
Contains a morpholine ring with a 2-bromo-6-methoxyphenyl group attached
Uses
Commonly used in pharmaceutical and medicinal research as a potential building block for the synthesis of biologically active molecules
Properties
Studied for potential antiviral, antifungal, and anti-inflammatory properties
Value
Considered a valuable intermediate in organic synthesis due to versatile reactivity and potential applications in drug discovery and development
Check Digit Verification of cas no
The CAS Registry Mumber 1444746-97-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,4,7,4 and 6 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1444746-97:
(9*1)+(8*4)+(7*4)+(6*4)+(5*7)+(4*4)+(3*6)+(2*9)+(1*7)=187
187 % 10 = 7
So 1444746-97-7 is a valid CAS Registry Number.
1444746-97-7Relevant academic research and scientific papers
Synthesis of ortho -haloaminoarenes by aryne insertion of nitrogen-halide Bonds
Hendrick, Charles E.,Wang, Qiu
, p. 1059 - 1069 (2015/01/30)
A rapid and general access to ortho-haloaminoarenes has been developed by aryne insertion into N-chloramine, N-bromoamine, and N-iodoamine bonds via two complementary protocols harnessing fluoride-promoted 1,2-elimination of ortho-trimethylsilyl aryltriflates. Typically, electron-deficient N-chloramines effectively react with aryne intermediates generated at elevated temperature with CsF, while less stable N-haloamines are found more efficient under milder, TBAF-mediated aryne formation at room temperature. Both protocols demonstrate a good level of regioselectivity and functional group tolerance. Efforts to elucidate the mechanism of N-X insertion are also discussed. The practical value of this transformation is highlighted by rapid synthesis of novel analogues of the antipsychotic cariprazine.
