144494-01-9

Basic information

• Product Name: 2',3'-di-O-acetyl-5'-chloro-5'-deoxy-5'-<(4-methoxyphenyl)sulfinyl(5'S,S_S)>adenosine
• Synonyms: 2',3'-di-O-acetyl-5'-chloro-5'-deoxy-5'-<(4-methoxyphenyl)sulfinyl(5'S,S_S)>adenosine
• CAS NO: 144494-01-9
• Molecular Weight: 523.954
• Mol File: 144494-01-9.mol

Chemical Properties

• CAS DataBase Reference: 2',3'-di-O-acetyl-5'-chloro-5'-deoxy-5'-<(4-methoxyphenyl)sulfinyl(5'S,S_S)>adenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 2',3'-di-O-acetyl-5'-chloro-5'-deoxy-5'-<(4-methoxyphenyl)sulfinyl(5'S,S_S)>adenosine(144494-01-9)
• EPA Substance Registry System: 2',3'-di-O-acetyl-5'-chloro-5'-deoxy-5'-<(4-methoxyphenyl)sulfinyl(5'S,S_S)>adenosine(144494-01-9)

Safety Data

• Hazardous Substances Data: 144494-01-9(Hazardous Substances Data)

Upstream product

• 121517-95-1 2',3'-di-O-acetyl-5'-deoxy-5'-<(4-methoxyphenyl)sulfinyl>adenosine 
• 137103-06-1 5'-S-(4-methoxyphenyl)-5'-thioadenosine 
• 144493-94-7 2',3'-di-O-acetyl-5'-S-(4-methoxyphenyl)-5'-thioadenosine 

Downstream Products

• 144494-02-0 5'(S)-chloro-5'-deoxy-5'-<(4-methoxyphenyl)sulfinyl(S_S)>adenosine 
• 121517-95-1 2',3'-di-O-acetyl-5'-deoxy-5'-<(4-methoxyphenyl)sulfinyl(S_R)>adenosine 
• 144493-95-8 5'-deoxy-5'-<(4-methoxyphenyl)sulfinyl(S_R)>adenosine 

Relevant articles and documents

Nucleic Acid Related Compounds. 76. Synthesis of 5'(E and Z)-Chloro-4',5'-didehydro-5'-deoxyadenosines via Chlorination and Thermolysis of Adenosine 5'-Sulfoxides. Mechanism-Based Inhibition of S-Adenosyl-L-homocysteine Hydrolase

Treatment of 2',3'-di-O-acetyl-5'-S-(4-methoxyphenyl)-5'-thioadenosine (1a), or its sulfoxides 2a(SR) and 3a(SS), with iodobenzene dichloride and potassium carbonate in acetonitrile resulted in formation of the 5'-chloro(and 5',5'-di