1445086-17-8

Basic information

• Product Name: Methanesulfonato[di-t-butyl(n-butyl)phosphine](2'-amino-1,1'-biphenyl-2-yl)palladium(II) dichloromethane adduct, min. 98% [P(t-Bu)2(n-Bu) Palladacycle Gen. 3]
• Synonyms: Methanesulfonato(tri-t-butylphosphino)(2'-amino-1,1'-biphenyl-2-yl)palladium(II), 98% [P(t-Bu)3 Palladacycle Gen. 3];Methanesulfonato[di-t-butyl(n-butyl)phosphine](2'-amino-1,1'-biphenyl-2-yl)palladium(II) dichloromethane adduct, min. 98% [P(t-Bu)2(n-Bu) Palladacycle Gen. 3];P(t-Bu)3 Pd G3;Methanesulfonato(tri-t-butylphosphino)(2'-amino-1,1'-biphenyl-2-yl)palladium(II),[P(t-Bu)3 Palladacycle Gen. 3]
• CAS NO: 1445086-17-8
• Molecular Formula: C25H40NO3PPdS
• Molecular Weight: 0
• Mol File: 1445086-17-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: Methanesulfonato[di-t-butyl(n-butyl)phosphine](2'-amino-1,1'-biphenyl-2-yl)palladium(II) dichloromethane adduct, min. 98% [P(t-Bu)2(n-Bu) Palladacycle Gen. 3](CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonato[di-t-butyl(n-butyl)phosphine](2'-amino-1,1'-biphenyl-2-yl)palladium(II) dichloromethane adduct, min. 98% [P(t-Bu)2(n-Bu) Palladacycle Gen. 3](1445086-17-8)
• EPA Substance Registry System: Methanesulfonato[di-t-butyl(n-butyl)phosphine](2'-amino-1,1'-biphenyl-2-yl)palladium(II) dichloromethane adduct, min. 98% [P(t-Bu)2(n-Bu) Palladacycle Gen. 3](1445086-17-8)

Safety Data

• Hazardous Substances Data: 1445086-17-8(Hazardous Substances Data)

Usage

Reaction

Pd-catalyzed cross-coupling reaction of s-BuB(OH)2 and 4-chloroanisole. Pd-catalyzed cross-coupling reaction of secondary alkylboronic acids and aryl chlorides. Pd-catalyzed cross-coupling reaction of secondary alkyltrifluoroborates and aryl chlorides

Upstream product

• 1445085-50-6 [1,1'-biphenyl]-2-aminium methanesulfonate 
• 90-41-5 2-phenylaniline 
• 13716-12-6 tri-tert-butyl phosphine 
• 1435520-65-2 (2'-amino-1,1'-biphenyl-2-yl)methanesulfonatopalladium(II) dimer 

Relevant articles and documents

Design and preparation of new palladium precatalysts for C-C and C-N cross-coupling reactions

A series of easily prepared, phosphine-ligated palladium precatalysts based on the 2-aminobiphenyl scaffold have been prepared. The role of the precatalyst-associated labile halide (or pseudohalide) in the formation and stability of the palladacycle has been examined. It was found that replacing the chloride in the previous version of the precatalyst with a mesylate leads to a new class of precatalysts with improved solution stability and that are readily prepared from a wider range of phosphine ligands. The differences between the previous version of precatalyst and that reported here are explored. In addition, the reactivity of the latter is examined in a range of C-C and C-N bond forming reactions.