144535-07-9Relevant academic research and scientific papers
A short synthesis of (-)-(4R,5S)-sitophilure using the regio- And stereoselective reduction of 3-acyltetrahydrothiopyran-4-ones with baker's yeast
Fujisawa, Tamotsu,Mobele, Bingidimi I.,Shimizu, Makoto
, p. 5567 - 5570 (2007/10/02)
Bakers' yeast reduction of 3-acyltetrahydrothiopyran-4-ones is regio- and enantioselective, yielding predominantly (3R,4S)-3-acyl-4- hydroxytetrahydrothiopyranes with high optical purity. This reduction method coupled with the Raney-nickel desulfurization provides a ready access to the rice and maize weevils aggregation pheromone, (-)-(4R,5S)-sitophilure, in high optical purity.
