144536-41-4

Upstream product

• 144536-39-0 (E)-3-Methyl-4-oxo-pent-2-enoic acid cyclohexylamide 
• 108-91-8 cyclohexylamine 
• 71339-40-7 3-methyl-4-oxo-pent-2-enoic acid 
• 144536-40-3 (E)-5-Ethoxy-4-hydroxy-3,4-dimethyl-hexa-2,5-dienoic acid cyclohexylamide 

Downstream Products

• 144536-42-5 N-Cyclohexyl-2-((2R,3R)-3-hydroxy-2,3-dimethyl-4-oxo-tetrahydro-thiophen-2-yl)-acetamide 
• 144536-42-5 N-Cyclohexyl-2-((2S,3R)-3-hydroxy-2,3-dimethyl-4-oxo-tetrahydro-thiophen-2-yl)-acetamide 
• 144536-44-7 C₂₃H₃₀N₂O₅S 
• 144536-43-6 N-Cyclohexyl-2-{(2S,3R)-3-hydroxy-5-[(Z)-hydroxyimino]-2,3-dimethyl-4-oxo-tetrahydro-thiophen-2-yl}-acetamide 
• 144536-47-0 N-Cyclohexyl-2-((3S,4S)-4-hydroxy-3,4-dimethyl-2,5-dioxo-2λ⁴-[1,2]dithiolan-3-yl)-acetamide 
• 144536-46-9 N-Cyclohexyl-2-((3S,4S)-4-hydroxy-3,4-dimethyl-5-oxo-[1,2]dithiolan-3-yl)-acetamide 
• 144536-45-8 (2R,3R)-4-Cyclohexylcarbamoyl-2-hydroxy-3-mercapto-2,3-dimethyl-thiobutyric acid S-ethyl ester 

Relevant academic research and scientific papers

Synthetic Studies on Leinamycin. A Synthesis of the 1-Oxo-1,2-dithiolan-3-one Moiety

A synthesis of the 1-oxo-1,2-dithiolan-3-one moiety of antitumor antibiotic leinamycin (1) i described.An intramolecular delivery of a sulfur atom (7 to 8) and a facile Beckmann fragmentation (10 to 12) constitute the backbone of our synthesis.