1445679-86-6Relevant articles and documents
A green approach for the regio- and stereo-selective syntheses of (Z)-3-methyleneisoindoline-1-ones in aqueous medium
Chatterjee, Nivedita,Sarkar, Swarbhanu,Pal, Rammyani,Sen, Asish Kumar
, p. 3748 - 3751 (2013)
A high yielding novel methodology was developed for the regio- and stereo-selective syntheses of (Z)-3-methyleneisoindoline-1-ones from substituted 2-phenylethynyl benzamides, generated in situ from 2-(phenylcarbamoyl)phenyl-1- H-imidazole-1-sulfonates and corresponding alkyne by Cu-free Sonogashira cross-coupling-5-exo-dig-cyclization in aqueous medium under sonication. The compound could easily be purified by recrystallization from EtOAc without column chromatography.