1445745-37-8

Basic information

• Product Name: 2-phenyl-4,5-bis(4-(trifluoromethyl)phenyl)oxazole
• Synonyms: 2-phenyl-4,5-bis(4-(trifluoromethyl)phenyl)oxazole
• CAS NO: 1445745-37-8
• Molecular Weight: 433.353
• Mol File: 1445745-37-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-phenyl-4,5-bis(4-(trifluoromethyl)phenyl)oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-4,5-bis(4-(trifluoromethyl)phenyl)oxazole(1445745-37-8)
• EPA Substance Registry System: 2-phenyl-4,5-bis(4-(trifluoromethyl)phenyl)oxazole(1445745-37-8)

Safety Data

• Hazardous Substances Data: 1445745-37-8(Hazardous Substances Data)

Upstream product

• 73790-20-2 4,4'-bis(trifluoromethyl)benzil 
• 100-46-9 benzylamine 
• 455-19-6 4-Trifluoromethylbenzaldehyde 

Relevant articles and documents

A Divergent Approach to Indoles and Oxazoles from Enamides by Directing-Group-Controlled Cu-Catalyzed Intramolecular C-H Amination and Alkoxylation

A directing-group-controlled, copper-catalyzed divergent approach to indoles and oxazoles from enamides has been developed. The picolinamide-derived enamides undergo the intramolecular aromatic C-H amination in the presence of a Cu(OPiv)2 catalyst and an MnO2 oxidant to form the corresponding indoles in good yields. On the other hand, simpler aryl- or alkyl-substituted enamides are converted to the 2,4,5-trisubstituted oxazole frameworks via vinylic C-H alkoxylation under identical conditions. The copper catalysis can provide uniquely divergent access to indole and oxazole heteroaromatic cores of great importance in medicinal and material chemistry.