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GEA 3162, with the molecular formula C13H14F3NO3S, is a selective and potent inhibitor of the enzyme hedgehog acyltransferase (Hhat). This enzyme is crucial in the hedgehog signaling pathways, which are implicated in various biological processes and diseases. GEA 3162 has garnered attention for its potential therapeutic applications, particularly in the treatment of cancers and metabolic disorders, due to its ability to effectively inhibit the growth and proliferation of cancer cells and regulate lipid metabolism.

144575-47-3

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144575-47-3 Usage

Uses

Used in Oncology:
GEA 3162 is used as an anticancer agent for its potential therapeutic applications in treating various cancers such as pancreatic, breast, and lung cancers. It targets the hedgehog signaling pathways, which are often dysregulated in cancer, thereby inhibiting the growth and proliferation of cancer cells both in vitro and in vivo.
Used in Metabolic Disorders:
In the field of metabolic disorders, GEA 3162 is used as a regulator of lipid metabolism and adipogenesis. Its demonstrated ability to influence these processes suggests its potential use in the treatment of obesity and other metabolic conditions, offering a new avenue for managing such diseases.
Used in Pharmaceutical Research and Development:
GEA 3162 is utilized as a research tool in the development of targeted cancer therapies. Its selectivity and potency as an inhibitor of hedgehog acyltransferase make it a promising candidate for further investigation into its mechanisms of action and therapeutic efficacy in preclinical and clinical studies.

Check Digit Verification of cas no

The CAS Registry Mumber 144575-47-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,5,7 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 144575-47:
(8*1)+(7*4)+(6*4)+(5*5)+(4*7)+(3*5)+(2*4)+(1*7)=143
143 % 10 = 3
So 144575-47-3 is a valid CAS Registry Number.

144575-47-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name GEA 3162

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:144575-47-3 SDS

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