1445849-80-8

Basic information

• Product Name: 2-(p-tolyl)-3-(trifluoromethyl)naphthalene-1,4-dione
• Synonyms: 2-(p-tolyl)-3-(trifluoromethyl)naphthalene-1,4-dione
• CAS NO: 1445849-80-8
• Molecular Weight: 316.279
• Mol File: 1445849-80-8.mol

Chemical Properties

• CAS DataBase Reference: 2-(p-tolyl)-3-(trifluoromethyl)naphthalene-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(p-tolyl)-3-(trifluoromethyl)naphthalene-1,4-dione(1445849-80-8)
• EPA Substance Registry System: 2-(p-tolyl)-3-(trifluoromethyl)naphthalene-1,4-dione(1445849-80-8)

Safety Data

• Hazardous Substances Data: 1445849-80-8(Hazardous Substances Data)

Upstream product

• 887144-94-7 Togni's reagent II 
• 60544-08-3 2-(4-methylphenyl)naphthalene-1,4-dione 

Relevant articles and documents

Synthesis of Trifluoromethylated Naphthoquinones via Copper-Catalyzed Cascade Trifluoromethylation/Cyclization of 2-(3-Arylpropioloyl)benzaldehydes

A novel copper-catalyzed cascade trifluoromethylation/cyclization of 2-(3-arylpropioloyl)benzaldehydes is described, allowing a direct access to structurally diverse trifluoromethylated naphthoquinones under mild reaction conditions. It represents the first trans-acyltrifluoromethylation of internal alkynes.

Copper-catalyzed direct C-H trifluoromethylation of quinones

An efficient and practical methodology has been developed to introduce the CF3 group onto quinones through Cu(I)-catalyzed direct C-H trifluoromethylation of quinones.