1445889-98-4

Upstream product

• 205985-98-4 methyl 2-chlorobenzoylacetate 
• 1445889-92-8 methyl 3-(2-chlorophenyl)-1H-pyrazole-4-carboxylate 
• 1445889-96-2 3-(2-chlorophenyl)-1-(2-chloropyridin-4-yl)-1H-pyrazole-4-carboxylic acid 
• 1445889-94-0 methyl 3-(2-chlorophenyl)-1-(2-chloropyridin-4-yl)-1H-pyrazole-4-carboxylate 

Downstream Products

• 1445890-02-7 2-chloro-4-[3-(2-chlorophenyl)-4-(1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-1,2,4-triazol-3-yl)-1H-pyrazol-1-yl]pyridine 
• 1445888-35-6 1-(2-acetamidopyridin-4-yl)-3-(2-chlorophenyl)-1H-pyrazole-4-carboxamide 
• 1445890-00-5 2-chloro-4-[3-(2-chlorophenyl)-4-(1H-1,2,4-triazol-3-yl)-1H-pyrazol-1-yl]pyridine 
• 1445890-06-1 di-tert-butyl {[3-(2-chlorophenyl)-1-(2-chloropyridin-4-yl)-1H-pyrazol-4-yl]carbonyl}imidodicarbonate 
• 1445888-28-7 N-{4-[3-(2-chlorophenyl)-4-(1H-1,2,4-triazol-3-yl)-1H-pyrazol-1-yl]-5-methylpyridin-2-yl}acetamide 
• 1445890-08-3 N-{5-bromo-4-[3-(2-chlorophenyl)-4-(1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-1,2,4-triazol-3-yl)-1H-pyrazol-1-yl]pyridin-2-yl}acetamide 
• 1445888-41-4 N-{4-[3-(2-chlorophenyl)-4-(1H-1,2,4-triazol-3-yl)-1H-pyrazol-1-yl]pyridin-2-yl}acetamide 
• 1445890-04-9 N-{4-[3-(2-chlorophenyl)-4-(1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-1,2,4-triazol-3-yl)-1H-pyrazol-1-yl]pyridin-2-yl}acetamide 

Relevant academic research and scientific papers

HETEROARYLS AND USES THEREOF

This invention provides compounds of formula IB: and also provides compounds of formulas ID, IIB, VB, and IIC: wherein HY, R1, R2, G5, G6, G7, G8, and G9 are as described in the specification. The compounds are inhibitors of VPS34 and/or PI3K and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.