1445972-75-7

Basic information

• Product Name: C₁₂H₁₅NO₂S₂
• Synonyms: C₁₂H₁₅NO₂S₂
• CAS NO: 1445972-75-7
• Molecular Weight: 269.389
• Mol File: 1445972-75-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₅NO₂S₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₅NO₂S₂(1445972-75-7)
• EPA Substance Registry System: C₁₂H₁₅NO₂S₂(1445972-75-7)

Safety Data

• Hazardous Substances Data: 1445972-75-7(Hazardous Substances Data)

Upstream product

• 52096-71-6 2-<4-(Benzylthio)butyl>-1H-isoindole-1,3(2H)-dione 
• 1414792-73-6 benzyl(4-isothiocyanatobutyl)sulfane 
• 100056-21-1 4-(benzylthio)butan-1-amine 

Relevant articles and documents

Synthesis and biological evaluation of sulforaphane derivatives as potential antitumor agents

A series of sulforaphane derivatives were synthesized and evaluated in vitro for their cytotoxicity against five cancer cell lines (HepG2, A549, MCF-7, HCT-116 and SH-SY5Y). The pharmacological results showed that many of the derivatives displayed more potent cytotoxicity than sulforaphane (SFN). Furthermore, SFN and derivative 85 could induce cell cycle arrest at S or G2/M phase and cell apoptosis. SFN and 85 exhibited time- and dose-dependent activation on Nrf2 transcription factor, and 85 acted as a more potent Nrf2 inducer than SFN.