1445986-08-2Relevant academic research and scientific papers
A supramolecular DNA self-assembly based on β-cyclodextrin-adamantane complexation as a bioorthogonal sticky end motif
Chiba, Junya,Sakai, Ayumi,Yamada, Syogo,Fujimoto, Kazuhisa,Inouye, Masahiko
, p. 6454 - 6456 (2013)
We propose linear end-to-end assemblies of short DNA duplexes based on β-cyclodextrin-adamantane complexation. The assembled duplexes exhibited increased Tm values compared with those of the corresponding natural hybrids. Competition experiments with external guest molecules showed a substantial decrease in Tm of the terminal modified duplexes, suggesting the viability of inter-duplex complexation.
