144604-00-2

Basic information

• Product Name: Diltiazem Malate
• Synonyms: Diltiazem malate [USAN]; (+)-(2S,3S)-5-(2-(Dimethylamino)ethyl)-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate (ester),(S)-malate (1:1); 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-, (2S-cis)-, (S)-hydroxybutanedioate (1:1); Diltiazem malate; Tiamate; UNII-14Y6444DRP; 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(di-methylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-(2S-cis)-, (S)-hydoxybutanedioate (1:1); 2-hydroxybutanedioic acid - (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate (1:1); (2S)-2-hydroxybutanedioic acid - (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate (1:1)
• CAS NO: 144604-00-2
• Molecular Formula: C₂₆H₃₂N₂O₉S
• Molecular Weight: 548.6053
• Mol File: 144604-00-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 594.4°C at 760 mmHg
• Flash Point: 313.3°C
• Vapor Pressure: 4.27E-14mmHg at 25°C
• CAS DataBase Reference: Diltiazem Malate(CAS DataBase Reference)
• NIST Chemistry Reference: Diltiazem Malate(144604-00-2)
• EPA Substance Registry System: Diltiazem Malate(144604-00-2)

Safety Data

• Hazardous Substances Data: 144604-00-2(Hazardous Substances Data)

Usage

General Description

Diltiazem malate is a medication used to treat high blood pressure and chest pain (angina). It belongs to a class of drugs known as calcium channel blockers, which work by relaxing the blood vessels and reducing the heart's workload. Diltiazem malate specifically acts by inhibiting the movement of calcium ions into the smooth muscle cells of the heart and blood vessels, leading to decreased contraction and dilation of the blood vessels. This results in lower blood pressure and improved blood flow to the heart, reducing the frequency and severity of angina attacks. The medication is usually taken orally in the form of extended-release capsules or tablets and should be used as directed by a healthcare professional. Common side effects may include dizziness, headache, flushing, and constipation. It is important to discuss any existing medical conditions or medications with a doctor before starting diltiazem malate.