Basic information

Product Name: Diltiazem Malate
Synonyms: Diltiazem malate [USAN]; (+)-(2S,3S)-5-(2-(Dimethylamino)ethyl)-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate (ester),(S)-malate (1:1); 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(dimethylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-, (2S-cis)-, (S)-hydroxybutanedioate (1:1); Diltiazem malate; Tiamate; UNII-14Y6444DRP; 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-(2-(di-methylamino)ethyl)-2,3-dihydro-2-(4-methoxyphenyl)-(2S-cis)-, (S)-hydoxybutanedioate (1:1); 2-hydroxybutanedioic acid - (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate (1:1); (2S)-2-hydroxybutanedioic acid - (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate (1:1)
CAS NO:144604-00-2
Molecular Formula: C₂₆H₃₂N₂O₉S
Molecular Weight: 548.6053
EINECS: N/A
Product Categories: N/A
Mol File: 144604-00-2.mol

Chemical Properties

Melting Point: N/A
Boiling Point: 594.4°C at 760 mmHg
Flash Point: 313.3°C
Appearance: N/A
Density: N/A
Vapor Pressure: 4.27E-14mmHg at 25°C
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Diltiazem Malate(CAS DataBase Reference)
NIST Chemistry Reference: Diltiazem Malate(144604-00-2)
EPA Substance Registry System: Diltiazem Malate(144604-00-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 144604-00-2(Hazardous Substances Data)

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Usage
SDS
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144604-00-2 Usage

Uses

Used in Cardiovascular Medicine:
Diltiazem malate is used as an antihypertensive agent for treating high blood pressure. It helps in relaxing the blood vessels, thereby reducing the heart's workload and lowering blood pressure.
Diltiazem malate is also used as an antianginal agent for managing chest pain (angina). It improves blood flow to the heart by dilating the blood vessels, reducing the frequency and severity of angina attacks.
The medication is typically administered orally in the form of extended-release capsules or tablets and should be taken as directed by a healthcare professional. It is important to consult a doctor before starting diltiazem malate, especially if there are any existing medical conditions or other medications being used.
Common side effects of diltiazem malate may include dizziness, headache, flushing, and constipation. However, these side effects are generally mild and can be managed with proper medical guidance.

Check Digit Verification of cas no

The CAS Registry Mumber 144604-00-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,6,0 and 4 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 144604-00:
(8*1)+(7*4)+(6*4)+(5*6)+(4*0)+(3*4)+(2*0)+(1*0)=102
102 % 10 = 2
So 144604-00-2 is a valid CAS Registry Number.

144604-00-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	2-Hydroxysuccinic acid - (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4- methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl a cetate (1:1)

1.2 Other means of identification

Product number	-
Other names	-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:144604-00-2 SDS

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