144608-89-9Relevant academic research and scientific papers
Stereochemical consequences of the Lewis acid-promoted 3-aza-cope rearrangement of N-alkyl-N-allyl enamines
Cook, Ggregory R.,Stille, John R.
, p. 4105 - 4124 (2007/10/02)
Internal and relative asymmetric induction were examined for the electrophile promoted 3-aza-Cope rearrangement of substituted N-alkyl-N-allyl enamines. In general, internal asymmetric induction was highly variable, and was dependent both upon the nature
Studies of Regiospecific 3-Aza-Cope Rearrangement Promoted by Electrophilic Reagents
Barta, Nancy S.,Cook, Gregory R.,Landis, Margaret S.,Stille, John R.
, p. 7188 - 7194 (2007/10/02)
The 3-aza-Cope rearrangement of N-alkyl-N-allyl enamine substrates, which required temperatures of 250 deg C to proceed thermally, was promoted at 111 deg C in the presence of electrophilic reagents such as HCl (0.5 equiv), TiCl4 (0.2 equiv), AlMe3 (1.2 e
