1446090-77-2

Basic information

• Product Name: 5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one
• Synonyms: 5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one;BGB-283;BGB-283,GDC-0810
• CAS NO: 1446090-77-2
• Molecular Formula: C25H17F3N4O3
• Molecular Weight: 478.4226896
• Mol File: 1446090-77-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 651.9±65.0 °C(Predicted)
• Appearance: /
• Density: 1.72±0.1 g/cm3(Predicted)
• PKA: 10.16±0.10(Predicted)
• CAS DataBase Reference: 5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one(1446090-77-2)
• EPA Substance Registry System: 5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one(1446090-77-2)

Safety Data

• Hazardous Substances Data: 1446090-77-2(Hazardous Substances Data)

Usage

Description

5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one is a complex organic compound characterized by a naphthyridinone core, a benzofuran moiety, and a trifluoromethyl-benzo[d]imidazol-2-yl substituent. It features a cyclopropa structure and is a derivative of 1,8-naphthyridine. 5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one may hold potential in medicinal chemistry, particularly in drug discovery and development, due to its unique structural features and possible pharmacological properties.

Uses

Used in Medicinal Chemistry:
5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one is used as a potential candidate in drug discovery and development for its unique structural features and potential pharmacological properties. Its cyclopropa[b]benzofuran and trifluoromethyl-benzo[d]imidazol-2-yl substituent may contribute to its biological activity, making it a promising compound for further research and development in the pharmaceutical industry.
Used in Drug Discovery:
In the field of drug discovery, 5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one is used as a starting point for the design and synthesis of new drugs. Its structural features, including the naphthyridinone core and the benzofuran moiety, may provide a foundation for the development of novel therapeutic agents with improved efficacy and selectivity.
Used in Pharmaceutical Development:
5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one is used in pharmaceutical development to explore its potential as a therapeutic agent. Further research is necessary to understand its biological activity, pharmacokinetics, and safety profile, which will help in optimizing its properties and evaluating its suitability for clinical applications.
Used in Research and Development:
In the research and development sector, 5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one is used to investigate its potential applications in various therapeutic areas. Its unique structure and potential pharmacological properties make it an interesting compound for studying its interactions with biological targets and evaluating its efficacy in treating specific diseases or conditions.
Used in Chemical Synthesis:
5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one is used in chemical synthesis to explore its reactivity and potential for the formation of new compounds with improved properties. Its cyclopropa structure and the presence of various functional groups make it a versatile building block for the synthesis of novel molecules with potential applications in various fields, including pharmaceuticals, materials science, and agrochemistry.