1446146-99-1Relevant articles and documents
Synthesis of spirocyclic indolines by interruption of the Bischler-Napieralski reaction
Medley, Jonathan William,Movassaghi, Mohammad
supporting information, p. 3614 - 3617 (2013/08/23)
The development of a versatile method for the synthesis of spirocyclic pyrrolidinoindolines is discussed. Treatment of N-acyltryptamines with trifluoromethanesulfonic anhydride-2-chloropyridine reagent combination affords highly persistent spiroindoleninium ions that are subject to intra- and intermolecular addition at C2 by nucleophiles.