144616-79-5Relevant academic research and scientific papers
Synthesis of 3-[α-(3-Chloro-2-oxo-4-substituted-phenyl/furfuryl-1-azetidinyl)]-2H-1- benzopyran-2-ones and 3-[α-(2-Substituted-phenyl/furfurylthiazolidiznyl)]-2H-1-benzopyran-2-ones as C.N.S. -active Agents
Kulkarni,Srivastava,Bishnoi, Abha,Dua
, p. 173 - 175 (2007/10/03)
Reaction of 3-substituted-phenylidine/furfurylidineamino-2H-1-benzopyran-2-ones (3a-d) with chloroacetyl chloride and thioglycolic acid affords the corresponding four-membered azetidinones (4a-d) and five-membered thiazolidinones (5a-d) respectively. All the compounds were tested for their acute toxicity, effects on gross behaviour, spontaneous motor activity (SMA), anorexigenic activity, neuroleptic activity and anticonvulsant activity. Compounds 4a and 5d exhibited C.N.S. depressant activity.
