1446200-52-7Relevant articles and documents
2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide derivatives as potent inhibitors of CK1δ/ε
Bischof, Joachim,Leban, Johann,Zaja, Mirko,Grothey, Arnhild,Radunsky, Barbara,Othersen, Olaf,Strobl, Stefan,Vitt, Daniel,Knippschild, Uwe
, p. 1577 - 1591 (2012)
In this study we identified two heterocyclic compounds (5 and 6) as potent and specific inhibitors of CK1δ (IC50 = 0.040 and 0.042 μM, respectively). Whereas compound 5 exhibited fivefold higher affinity towards CK1δ than to CK1ε (IC50/su