1446253-32-2Relevant academic research and scientific papers
Synthesis of Pyridyl-4-Oxy-Substituted N-Hydroxy Amides of Cinnamic Acid as New Inhibitors of Histone Deacetylase Activity and Hepatitis C Virus Replication
Kozlov,Malikova,Kamarova,Konduktorov,Kochetkov
, (2018)
Three structural isomers of pyridyl-4-oxy-substituted N-hydroxy amides of cinnamic acid (PyOCHA) have been synthesized for the first time. The relationship between their antiviral activity against hepatitis C virus (HCV) and inhibition of histone deacetyl
CINNAMIC ACID HYDROXYAMIDES AS INHIBITORS OF HISTONE DEACETYLASE 8
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Paragraph 00367, (2013/07/19)
Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activy of histone deacetylase 8 (HDAC8). Also described herein are methods of using such HDAC8 inhibitors, alone and in combination with other comp
