1446271-34-6

Basic information

• Product Name: (R,E)-2-(3-(2-oxo-2-phenylethyl)-5-phenylpent-4-enoyl)pyridine1-oxide
• CAS NO: 1446271-34-6
• Molecular Weight: 371.436
• Mol File: 1446271-34-6.mol

Chemical Properties

• CAS DataBase Reference: (R,E)-2-(3-(2-oxo-2-phenylethyl)-5-phenylpent-4-enoyl)pyridine1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (R,E)-2-(3-(2-oxo-2-phenylethyl)-5-phenylpent-4-enoyl)pyridine1-oxide(1446271-34-6)
• EPA Substance Registry System: (R,E)-2-(3-(2-oxo-2-phenylethyl)-5-phenylpent-4-enoyl)pyridine1-oxide(1446271-34-6)

Safety Data

• Hazardous Substances Data: 1446271-34-6(Hazardous Substances Data)

Upstream product

• 13735-81-4 1-styrenyloxytrimethylsilane 
• 1261559-66-3 (E,E)-2-(5-phenyl-2,4-pentadienoyl)pyridine N-oxide 

Relevant articles and documents

Enantioselective Mukaiyama-Michael with 2-enoyl pyridine N-oxides catalyzed by PYBOX-DIPH-Zn(ii)-complexes at ambient temperature

A chiral PYBOX-DIPH-Zn(ii) catalyzed enantioselective Mukaiyama-Michael reaction of acyclic silyl enol ethers with 2-enoylpyridine N-oxides has been studied in external additive free conditions at ambient temperature. The methodology offers straightforward access to a variety of functionalized chiral 1,5-dicarbonyl compounds, which could easily be elaborated into synthetically viable pyrones via hydrolysis followed by cyclization. A transition state model has been proposed to explain the stereochemical outcome. The Royal Society of Chemistry 2013.