Ald-PEG5-t-butyl ester, also known as Ald-CH2-PEG5-t-butyl ester, is an aldehyde PEG linker that is specifically reactive with aminooxy-containing molecules. Ald-PEG5-t-butyl ester features a PEG5 spacer, which enhances its aqueous solubility, and a t-butyl ester group that can be removed under acidic conditions to allow for further conjugation. Due to its unique properties, Ald-PEG5-t-butyl ester holds potential in various applications across different industries.
1446282-23-0
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Basic information
- Product Name: Ald-PEG5-t-butyl ester
- Synonyms: Ald-PEG5-t-butyl ester;Ald-CH2-PEG5-CH2CH2COOtBu
- CAS NO:1446282-23-0
- Molecular Formula: C17H32O8
- Molecular Weight: 364.43
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Ald-PEG5-t-butyl ester(CAS DataBase Reference)
- NIST Chemistry Reference: Ald-PEG5-t-butyl ester(1446282-23-0)
- EPA Substance Registry System: Ald-PEG5-t-butyl ester(1446282-23-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1446282-23-0(Hazardous Substances Data)
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1446282-23-0 Usage
Uses
Used in Pharmaceutical Industry:Ald-PEG5-t-butyl ester is used as a molecular linker for the conjugation of therapeutic agents to targeting molecules. Its ability to react with aminooxy-containing molecules allows for the creation of targeted drug delivery systems, which can improve the efficacy and specificity of treatments.
Used in Chemical Synthesis:
Ald-PEG5-t-butyl ester serves as a versatile building block in the synthesis of complex molecules and polymers. The t-butyl ester group can be selectively removed under acidic conditions, enabling further functionalization and modification of the molecule.
Used in Bioconjugation:
In the field of bioconjugation, Ald-PEG5-t-butyl ester is used as a reactive intermediate for the attachment of biologically active molecules to various scaffolds. The PEG5 spacer improves the solubility and stability of the final conjugate, while the aldehyde group facilitates the coupling process.
Used in Drug Delivery Systems:
Ald-PEG5-t-butyl ester is employed as a component in the design of drug delivery systems, particularly for enhancing the solubility and bioavailability of hydrophobic drugs. The PEG5 spacer can also help to reduce the immunogenicity and increase the circulation time of the drug in the body.
Used in Material Science:
In material science, Ald-PEG5-t-butyl ester can be utilized in the development of novel materials with enhanced properties, such as improved hydrophilicity, biocompatibility, and controlled release capabilities. The compound's reactivity and PEGylation potential make it a valuable asset in the creation of advanced materials for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1446282-23-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,4,6,2,8 and 2 respectively; the second part has 2 digits, 2 and 3 respectively.Calculate Digit Verification of CAS Registry Number 1446282-23:
(9*1)+(8*4)+(7*4)+(6*6)+(5*2)+(4*8)+(3*2)+(2*2)+(1*3)=160
160 % 10 = 0
So 1446282-23-0 is a valid CAS Registry Number.
1446282-23-0Upstream product
1446282-23-0Downstream Products
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Ald-PEG5-t-butyl ester
