1446282-28-5

Basic information

• Product Name: PEG5-bis-(ethyl phosphonate)
• Synonyms: PEG5-bis-(ethyl phosphonate)
• CAS NO: 1446282-28-5
• Molecular Formula: C20H44O11P2
• Molecular Weight: 522.504282
• Mol File: 1446282-28-5.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: PEG5-bis-(ethyl phosphonate)(CAS DataBase Reference)
• NIST Chemistry Reference: PEG5-bis-(ethyl phosphonate)(1446282-28-5)
• EPA Substance Registry System: PEG5-bis-(ethyl phosphonate)(1446282-28-5)

Safety Data

• Hazardous Substances Data: 1446282-28-5(Hazardous Substances Data)

Usage

Description

PEG5-bis-(ethyl phosphonate) is a PEG (polyethylene glycol) linker that features two ethyl phosphonate moieties attached to it. This molecular structure is designed to enhance the solubility of compounds in aqueous environments due to the hydrophilic nature of the PEG linker.

Uses

Used in Pharmaceutical Industry:
PEG5-bis-(ethyl phosphonate) is used as a solubility enhancer for improving the aqueous solubility of poorly water-soluble drugs. The increased solubility can lead to better bioavailability and therapeutic efficacy of the drug.
Used in Drug Delivery Systems:
In the field of drug delivery, PEG5-bis-(ethyl phosphonate) serves as a versatile linker that can be used to conjugate drugs with targeting moieties or other functional groups. This modification can enhance the drug's targeting capabilities, reduce off-target effects, and improve overall pharmacokinetic properties.
Used in Bioconjugation:
PEG5-bis-(ethyl phosphonate) is used as a bioconjugation agent to attach biologically active molecules, such as peptides, proteins, or nucleic acids, to various surfaces or other molecules. The PEG linker can provide stability and solubility benefits, while the phosphonate groups facilitate covalent attachment.
Used in Material Science:
In material science, PEG5-bis-(ethyl phosphonate) can be utilized as a building block for the development of novel materials with tailored properties. The hydrophilic PEG linker can improve the compatibility of the material with biological systems, making it suitable for applications in biocompatible coatings or hydrogels.
Used in Chemical Synthesis:
As an intermediate in chemical synthesis, PEG5-bis-(ethyl phosphonate) can be employed to create a variety of complex molecules with specific functions. The ethyl phosphonate moieties can participate in various chemical reactions, allowing for the synthesis of diverse compounds with potential applications in different industries.