144632-52-0Relevant academic research and scientific papers
Asymmetric Michael addition of aldehydes to nitroalkenes using a primary amino acid lithium salt
Yoshida, Masanori,Sato, Atsushi,Hara, Shoji
experimental part, p. 3031 - 3036 (2010/09/06)
Enantioselective Michael addition of aldehydes to nitroalkenes was successfully carried out by asymmetric catalysis with l-phenylalanine lithium salt, giving γ-nitroaldehydes in good yields with high enantioselectivity.
A chiral primary amine thiourea catalyst for the highly enantioselective direct conjugate addition of α,α-disubstituted aldehydes to nitroalkenes
Lalonde, Mathieu P.,Chen, Yonggang,Jacobsen, Eric N.
, p. 6366 - 6370 (2007/10/03)
(Chemical Equation Presented) Dual activation: The bifunctional primary amine thiourea catalyst 1 promotes the highly enantioselective direct conjugate addition of α-branched aldehydes to nitroalkenes (see scheme). Cooperative activation of both the nucleophile and electrophile allows the use of mild reaction conditions and provides access to a wide variety of adducts with vicinal quaternary and tertiary stereogenic centers (>90% ee).
Michael additions of aldehydes and ketones to β-nitrostyrenes in an ionic liquid
Kotrusz, Peter,Toma, Stefan,Schmalz, Hans-Guenther,Adler, Andreas
, p. 1577 - 1583 (2007/10/03)
Michael additions of different aldehydes and ketones to β-nitrostyrene and 2-(β-nitrovinyl)thiophene in 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim]PF6) were studied. β-Nitrostyrene was a better acceptor than 2-(β-nitrovinyl)thiophen
N-(2-Phenylprop-1-enyl)proline Methyl Ester: Equilibrium between the Enamine and the Aza Methine Ylide Form
Felluga, Fulvia,Nitti, Patrizia,Pitacco, Giuliana,Valentin, Ennio
, p. 2331 - 2336 (2007/10/02)
The title compound reacted with nitroolefins to give either cyclobutanes or pyrrolizidine derivatives, depending on whether it acted as an enamine or as a 1,3-dipole.
