144637-68-3

Basic information

• Product Name: ALPHA-DENDROTOXIN
• Synonyms: ALPHA-DTX;ALPHA-DENDROTOXIN;PYR-PRO-ARG-ARG-LYS-LEU-CYS-ILE-LEU-HIS-ARG-ASN-PRO-GLY-ARG-CYS-TYR-ASP-LYS-ILE-PRO-ALA-PHE-TYR-TYR-ASN-GLN-LYS-LYS-LYS-GLN-CYS-GLU-ARG-PHE-ASP-TRP-SER-GLY-CYS-GLY-GLY-ASN-SER-ASN-ARG-PHE-LYS-THR-ILE-GLU-GLU-CYS-ARG-ARG-THR-CYS-ILE-GLY-OH
• CAS NO: 144637-68-3
• Molecular Weight: 0
• Mol File: 144637-68-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: ALPHA-DENDROTOXIN(CAS DataBase Reference)
• NIST Chemistry Reference: ALPHA-DENDROTOXIN(144637-68-3)
• EPA Substance Registry System: ALPHA-DENDROTOXIN(144637-68-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 144637-68-3(Hazardous Substances Data)

Usage

General Description

Alpha-dendrotoxin is a toxic peptide that is derived from the green mamba snake (Dendroaspis angusticeps). It is known for its potent neurotoxic effects, particularly on voltage-gated potassium channels in the central nervous system. The toxin specifically targets certain subtypes of potassium channels, leading to the inhibition of neurotransmitter release and ultimately causing paralysis and death in its prey. Alpha-dendrotoxin has been studied extensively for its potential therapeutic uses, particularly in the field of neuroscience and as a tool for research on potassium channel function and structure. Its unique mechanism of action and high affinity for potassium channels make it an important tool in studying the physiological and pathological roles of these channels in the central nervous system.