14464-90-5Relevant articles and documents
A new lignan glycoside and phenylethanoid glycosides from Strobilanthes cusia BREMEK
Tanaka, Tomonori,Ikeda, Tsuyoshi,Kaku, Miho,Zhu, Xing-Hua,Okawa, Masafumi,Yokomizo, Kazumi,Uyeda, Masaru,Nohara, Toshihiro
, p. 1242 - 1245 (2004)
The root of Strobilanthes cusia BREMEK. (Acanthaceae), popularly known as Da-Ching-Yeh, has been commonly used in traditional Chinese medicine. It is used to treat influenza, epidemic cerebrospinal meningitis, encephalitis B, viral pneumonia, mumps, and severe acute respiratory syndrome (SARS). In this study, we found a new lignan glycoside (6) and two new phenylethanoid glycosides (7, 8) together with five known compounds as chemical constituents of Strobilanthes cusia root. Some samples were examined for anti-herpes simplex virus type-1 (HSV-1) activity. Among the tested samples, lupeol showed anti-HSV-1 activity (EC50: 11.7 μM) and showed 100% inhibition of virus plaque formation at 58.7 μM.
Phenolic constituents from the twigs of Betula schmidtii collected in Goesan, Korea
Park, Kyoung Jin,Cha, Joon Min,Subedi, Lalita,Kim, Sun Yeou,Lee, Kang Ro
, (2019)
Six undescribed phenolic derivatives along with thirty two known compounds were isolated from the twigs of Betula schmidtii. The chemical structures were characterized through extensive spectroscopic analysis and chemical methods. All known compounds were first isolated in this plant. The anti-inflammatory effect of the isolates was tested by measuring nitric oxide production in lipopolysaccharide-activated BV-2 cells. Isotachioside, 4-allyl-2-hydrophenyl 1-O-β-D-apiosyl-(1 → 6)-β-D-glucopyranoside, genistein 5-O-β-D-glucoside, and prunetinoside showed a slight potency to lower the NO production against LPS-activated microglia with IC50 values of 23.9, 25.3, 28.8, and 34.0 μM, respectively.
Indonesian medicinal plants. XII. Four isomeric lignan-glucosides from the bark of Aegle marmelos (Rutaceae)
Ohashi,Watanabe,Okumura,Uji,Kitagawa
, p. 1924 - 1926 (1994)
From the bark of Aegle marmelos Correa (Rutaceae), an Indonesian medicinal plant, two new lignan-glucosides, ( )-lyoniresinol 2α-O-β-D-glucopyranoside (3) and (-)-4-epi-lyoniresinol 3α-O-β-D-glucopyranoside (4), have been isolated together with two known lignan-glucosides, (+)-lyoniresinol 3α-O-β-D-glucopyranoside (1) and (-)lyoniresinol 3α-O-β-D-glucopyranoside (2).
Novel tetrahydrofuran structures derived from β-β-coupling reactions involving sinapyl acetate in Kenaf lignins
Lu, Fachuang,Ralph, John
experimental part, p. 3681 - 3694 (2009/02/05)
Free radical coupling of sinapyl γ-acetate or cross-coupling between sinapyl acetate and sinapyl alcohol yields novel tetrahydrofuran β-β-(cross-)coupled dehydrodimers. Such substructures are therefore anticipated in naturally acetylated lignins, e.g. in Kenaf, if sinapyl acetate is a component of the lignin monomer pool. The DFRC (derivatization followed by reductive cleavage) method, modified by replacing all acetyl reagents and solvents with their propionyl analogs (DFRC′), allows the analysis of naturally acetylated lignins. DFRC′ treatment of the sinapyl acetate-derived dimers or crossed dimers gave diagnostic products that retain at least one acetate group on a sidechain γ-position; the products have been authenticated by comparison of their mass spectra and GC retention times with those of synthesized compounds. DFRC′ of Kenaf lignins produces the same diagnostic products as from the dimers, implicating the presence of the various tetrahydrofuran units in Kenaf lignins. With data from the model compounds in hand, NMR analysis of Kenaf lignins elegantly confirms the presence of such substructures in the polymer, establishing that acetates on Kenaf lignins arise through incorporation of sinapyl acetate, as a lignin precursor, via enzyme-mediated radical coupling mechanisms. The Royal Society of Chemistry 2008.
