1446417-86-2

Basic information

• Product Name: 1-(4-chlorophenyl)-2-fluoroethan-1-ol
• Synonyms: 1-(4-chlorophenyl)-2-fluoroethan-1-ol
• CAS NO: 1446417-86-2
• Molecular Weight: 174.602
• Mol File: 1446417-86-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(4-chlorophenyl)-2-fluoroethan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)-2-fluoroethan-1-ol(1446417-86-2)
• EPA Substance Registry System: 1-(4-chlorophenyl)-2-fluoroethan-1-ol(1446417-86-2)

Safety Data

• Hazardous Substances Data: 1446417-86-2(Hazardous Substances Data)

Upstream product

• 99-91-2 para-chloroacetophenone 
• 2881-63-2 ethyl (4-chlorobenzoyl)acetate 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 329-78-2 1-(4-chlorophenyl)-2-fluoroethan-1-one 

Relevant articles and documents

Double Enzyme-Catalyzed One-Pot Synthesis of Enantiocomplementary Vicinal Fluoro Alcohols

A double-enzyme-catalyzed strategy for the synthesis of enantiocomplementary vicinal fluoro alcohols through a one-pot, three-step process including lipase-catalyzed hydrolysis, spontaneous decarboxylative fluorination, and subsequent ketoreductase-catalyzed reduction was developed. With this approach, β-ketonic esters were converted to the corresponding vicinal fluoro alcohols with high isolated yields (up to 92percent) and stereoselectivities (up to 99percent). This new cascade process addresses some issues in comparison with traditional methods such as environmentally hazardous reaction conditions and low stereoselectivity outcome.