1446427-80-0

Basic information

• Product Name: 7-bromo-2-imino-N-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2H-chromene-3-carboxamide
• Synonyms: 7-bromo-2-imino-N-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2H-chromene-3-carboxamide
• CAS NO: 1446427-80-0
• Molecular Weight: 415.27
• Mol File: 1446427-80-0.mol

Chemical Properties

• CAS DataBase Reference: 7-bromo-2-imino-N-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2H-chromene-3-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 7-bromo-2-imino-N-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2H-chromene-3-carboxamide(1446427-80-0)
• EPA Substance Registry System: 7-bromo-2-imino-N-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2H-chromene-3-carboxamide(1446427-80-0)

Safety Data

• Hazardous Substances Data: 1446427-80-0(Hazardous Substances Data)

Upstream product

• 22532-62-3 4-bromosalicylaldehyde 
• 1446427-77-5 2-cyano-N-(2-mercapto-1H-benzo[d]imidazol-5-yl)acetamide 

Relevant articles and documents

Synthesis and biological evaluation of benzo[d]imidazolyl chromeno[2,3-d]pyrimidinones

A series of benzo[d]imidazolyl chromeno[2,3-d]pyrimidnones were described. The key intermediate 2-cyano-N-(2-mercapto-1H-benzo[d]imidazol-5-yl)acetamide (3) is obtained by reacting 5-amino-2-mercaptobenzimidazole (1) with ethyl cyanoacetate (2). Compound 3 on reaction with substituted salicylaldehydes afforded 2-imino-N-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2H-chromene-3- carboxamides (5) in good yields. Compounds 5 on condensation with formalin furnished the title compounds viz., 3-(2-mercapto-1H-benzo[d]imidazol-5-yl)-2H- chromeno[2,3-d]pyrimidin-4(3H)-ones (7). All the synthesized compounds were screened for their anti-microbial and anti-oxidant activities.