144650-95-3

Basic information

• Product Name: SASD
• Synonyms: SASD;SULFOSUCCINIMIDYL 2-(P-AZIDOSALICYLAMIDO) ETHYL-1,3'-DITHIOPROPIONATE;SULFOSUCCINIMIDYL-2-(P-AZIDOSALICYLAMIDO)ETHYL-1,3-DITHIOPROPIONATE;SULFO SASD;SULFO-N-SUCCINIMIDYL3-[[2-(P-AZIDOSALICYLAMIDO)ETHYL]-1,3'-DITHIO]PROPIONATE;3-[[2-[(4-Azido-2-hydroxybenzoyl)aMino]ethyl]dithio]propanoic Acid 2,5-Dioxo-3-sulfo-1-pyrrolidinyl Ester;SulfosucciniMidyl 2-(p-azido-salicylaMido)ethyl 1,3`-dithiopropionate(Sulfo-SASD);SASD (SulfosucciniMidyl-2-(p-azidosalcylaMido)ETHYL-1,3-DITHIOPROPIONATE)
• CAS NO: 144650-95-3
• Molecular Formula: C16H16N5NaO9S3
• Molecular Weight: 541.51
• Product Categories: Cross Linking Reagents;MTS & Sulfhydryl Active Reagents;Photoaffinity Labels
• Mol File: 144650-95-3.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: 0-6°C
• Solubility: DMSO, Hot Water
• Stability: Light Sensitive
• CAS DataBase Reference: SASD(CAS DataBase Reference)
• NIST Chemistry Reference: SASD(144650-95-3)
• EPA Substance Registry System: SASD(144650-95-3)

Safety Data

• Hazardous Substances Data: 144650-95-3(Hazardous Substances Data)

Usage

Description

SASD, also known as a photo-reactive heterobifunctional cross-linker, is a chemical compound that features hydroxyphenyl azide and Sulfo-NHS ester reactive groups. It is characterized by its light brown powder appearance and a spacer arm of 18.9 Angstroms. SASD is utilized in various applications due to its unique properties, making it a versatile tool in different industries.

Uses

Used in Bioconjugation Applications:
SASD is used as a cross-linking agent for bioconjugation purposes, allowing the selective and efficient coupling of biomolecules such as proteins, peptides, and antibodies. Its photo-reactive nature enables the formation of stable covalent bonds upon exposure to light, facilitating the creation of well-defined and stable bioconjugates.
Used in Iodination Reactions:
SASD is employed as a reagent in iodination reactions, where it can be used to introduce radioactive or non-radioactive iodine atoms into biomolecules. This is particularly useful in the fields of medical imaging, diagnostics, and radiopharmaceutical development, as well as in the synthesis of iodinated contrast agents for various imaging techniques.
Used in Research and Development:
In the research and development industry, SASD is used as a valuable tool for studying the structure, function, and interactions of biomolecules. Its ability to form covalent bonds with high specificity and efficiency makes it an essential component in the development of novel bioconjugates and the investigation of biomolecular interactions.
Used in Pharmaceutical Industry:
SASD is utilized in the pharmaceutical industry for the development of drug delivery systems and targeted therapies. Its cross-linking capabilities enable the creation of drug conjugates with improved stability, solubility, and targeted delivery, potentially enhancing the efficacy and safety of various therapeutic agents.
Used in Diagnostics:
In the diagnostics field, SASD is employed for the development of diagnostic tools and assays that rely on the specific binding and detection of biomolecules. Its ability to form stable bioconjugates makes it a valuable component in the creation of highly sensitive and specific diagnostic tests for various diseases and conditions.
Overall, SASD is a versatile and valuable compound with a wide range of applications across different industries, including bioconjugation, iodination reactions, research and development, pharmaceuticals, and diagnostics. Its unique properties and capabilities make it an essential tool for scientists and researchers working with biomolecules and related applications.