1446678-06-3

Basic information

• Product Name: C₂₃H₂₂ClF₃N₄O₃
• CAS NO: 1446678-06-3
• Molecular Weight: 494.901
• Mol File: 1446678-06-3.mol

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₂ClF₃N₄O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₂ClF₃N₄O₃(1446678-06-3)
• EPA Substance Registry System: C₂₃H₂₂ClF₃N₄O₃(1446678-06-3)

Safety Data

• Hazardous Substances Data: 1446678-06-3(Hazardous Substances Data)

Upstream product

• 298709-38-3 3,5-difluoropyridine-2-carboximidamide 
• 1233506-04-1 3-chloro-5-fluorophenylacetylene 
• 1446678-02-9 C₁₈H₁₃ClF₃N₃O₃ 

Relevant articles and documents

4,4-DISUBSTITUTED-1,4-DIHYDROPYRIMIDINES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B

Inhibitors of HBV replication of formula (I) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein R1-R5, B and Z have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.