1446748-41-9

Upstream product

• 1446748-36-2 C₂₅H₂₆N₂O₆ 
• 102229-10-7 2-(tert-butyldimethylsilyloxy)ethanol 
• 1446748-34-0 C₁₈H₂₀N₂O₆ 
• 1463-10-1 5-Methyluridine 

Downstream Products

• 1446748-43-1 C₄₈H₅₀N₂O₁₁ 
• 1446748-44-2 C₅₅H₅₆N₂O₁₃S 
• 1446748-45-3 C₄₈H₄₈N₂O₁₀ 
• 1446748-47-5 C₃₃H₃₄N₂O₉ 
• 1446748-48-6 C₄₂H₅₁N₄O₁₀P 
• 1446748-42-0 C₅₄H₆₄N₂O₁₁Si 

Relevant academic research and scientific papers

Synthesis and properties of 2′- O,4′- C -ethyleneoxy bridged 5-methyluridine

2′-O,4′-C-Ethyleneoxy bridged 5-methyluridine (EoNA-T), possessing a seven-membered linkage and an anomeric 4′-carbon, was synthesized and introduced into oligonucleotides by using an automated DNA synthesizer. The EoNA-modified oligonucleotides significantly stabilized the duplexes with single-stranded RNA and triplexes with double-stranded DNA relative to the natural oligonucleotide and oligonucleotides modified by another seven-membered bridged 5-methyluridine, 2′,4′-BNACOC-T. In addition, EoNA-T showed excellent nuclease resistance.