1446826-52-3

Basic information

• Product Name: C₂₂H₂₅Cl₂N₃O₃
• Synonyms: C₂₂H₂₅Cl₂N₃O₃
• CAS NO: 1446826-52-3
• Molecular Weight: 450.365
• Mol File: 1446826-52-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₂₅Cl₂N₃O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₂₅Cl₂N₃O₃(1446826-52-3)
• EPA Substance Registry System: C₂₂H₂₅Cl₂N₃O₃(1446826-52-3)

Safety Data

• Hazardous Substances Data: 1446826-52-3(Hazardous Substances Data)

Upstream product

• 119532-26-2 1-(2,3-dichlorophenyl)-piperazine hydrochloride 
• 1421851-54-8 C₁₂H₁₄BrNO₃ 
• 6253-28-7 exo-7-oxabicyclo[2.2.1]hept-4-ene-2,3-dicarboximide 

Relevant articles and documents

Synthesis of new aryl(hetaryl)-substituted tandospirone analogues with potential anxiolytic activity via reductive Heck type hydroarylations

Tandospirone (I), developed as an anxiolytic drug, is an aryl-piperazine compound that binds to both 5-HT1A and dopamine D4 receptors. Palladium-catalysed hydroarylation reactions of tandospirone analogues containing an oxygen bridge and 3-(trifluoromethyl)phenyl or 2,3-dichlorophenyl groups were studied in order to find a new stereoselective access to a series of new exo-aryl(hetaryl)-substituted derivatives with potential biological activity.