144689-79-2 Usage
Imidazole ring
The core structure of the compound, consisting of a five-membered ring with two nitrogen atoms and one hydrogen atom.
Carboxylic acid group
A functional group (-COOH) attached to the imidazole ring, contributing to the compound's acidity and potential for forming salts or esters.
Propyl side chain
A three-carbon alkyl chain (-CH2-CH2-CH3) attached to the imidazole ring, which may influence the compound's lipophilicity and solubility.
1-hydroxy-1-methylethyl side chain
A bulky side chain (-CH2OH-CH(CH3)-) connected to the propyl chain, which can affect the compound's steric properties and interactions with other molecules.
Tetrazolyl-biphenyl compound
A heterocyclic ring system (1H-tetrazol-5-yl) connected to a biphenyl group (two phenyl rings), which may contribute to the compound's biological activity and selectivity.
Ethoxycarbonyl functional group
An ester-forming group (-COOCH2CH3) derived from ethanol, which connects the carboxylic acid group to the rest of the molecule and classifies the compound as an ester.
Ester classification
The presence of the ethoxycarbonyl group indicates that the compound is an ester, which may have applications in pharmaceutical or industrial settings.
Potential pharmaceutical or industrial applications
Due to its complex structure and the presence of various functional groups, the compound may have potential uses in drug development or other industrial processes, such as catalysts or dyes.
Check Digit Verification of cas no
The CAS Registry Mumber 144689-79-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,6,8 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 144689-79:
(8*1)+(7*4)+(6*4)+(5*6)+(4*8)+(3*9)+(2*7)+(1*9)=172
172 % 10 = 2
So 144689-79-2 is a valid CAS Registry Number.
144689-79-2Relevant academic research and scientific papers
ANGIOTENSIN II ANTAGONIST 1-BIPHENYLMETHYLIMIDAZOLE COMPOUNDS AND THEIR THERAPEUTIC USE
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, (2008/06/13)
Compounds of the following formula (I) or the formula (I) p : STR1 wherein R 1 is alkyl or alkenyl; R 2 and R 3 are hydrogen, alkyl, alkenyl, cycloalkyl, aralkyl, aryl, or aryl fused to cycloalkyl; R 4 is hydrogen, alkyl, alkanoyl, alkenoyl, arylcarbonyl, alkoxycarbonyl, tetrahydropyranyl, tetrahydrothiopyranyl, tetrahydrothienyl, tetrahydrofuryl, a group of formula--SiR a R b R c, in which R a, R b and R c are alkyl or aryl, alkoxymethyl, (alkoxyalkoxy)methyl, haloalkoxymethyl, aralkyl, aryl or alkanoyloxymethoxycarbonyl; R 5 is carboxy or--CONR 8 R 9, wherein R 8 and R 9 hydrogens or alkyl, or R 8 and R 9 together form alkylene; R 6 is hydrogen, alkyl, alkoxy or halogen; R. sup.7 is carboxy or tetrazol-5-yl; R p. sup.1 is hydrogen, alkyl, cycloalkyl or alkanoyl; R p 2 is a single bond, alkylene or alkylidene; R p 3 and R p 4 are each hydrogen or alkyl; R. sub.p 6 is carboxy or tetrazol-5-yl; and X p is oxygen or sulfur; and pharmaceutically acceptable salts and esters thereof. The compounds are AII receptor antagonists and thus have hypotensive activity and can be used for the treatment and prophylaxis of hypertension. The compounds may be prepared by reacting a biphenylmethyl compound with an imidazole compound.
