144693-92-5Relevant academic research and scientific papers
Direct β-Selective Cross-Coupling of Alkenyl Gold Complexes with Alkyl Electrophiles
Nguyen, Julia,Duncan, Nicole,Lalic, Gojko
, p. 5803 - 5806 (2016)
Alkenyl gold complexes are common intermediates in gold-catalyzed transformations of allenes and alkynes, and numerous methods for their functionalization have been explored. Particularly valuable are cross-coupling reactions, which result in the formation of a new C–C bond. Several strategies are known that enable α-selective cross-coupling of alkenyl gold complexes with aryl, allyl, or acyl coupling partners. We describe the direct β-selective cross-coupling of alkenyl gold complexes with simple alkyl electrophiles. We also describe the effects of the steric and electronic properties of alkenyl gold complexes on the selectivity of the cross-coupling reaction.
