144694-89-3Relevant academic research and scientific papers
Synthesis of enantiomerically pure 2,3-disubstituted oxirane-2- carboxamides
Garcia Ruano, Jose L.,Martin Castro, Ana M.,Rodriguez Ramos, Jesus H.,Rubio Flamarique, Ana C.
, p. 3503 - 3511 (2007/10/03)
The title compounds were efficiently prepared from l-alkyl(or phenyl)- 2-methyl-2-(tolylsulfinyl)ethanone through a simple four-step sequence: highly stereoselective hydrocyanation with Et2AlCN (key step to control the stereochemistry); hydroly
Highly Diastereoselective Hydrocyanation of β-Keto Sulfoxides: Synthesis of Enantiomerically Pure Cyanohydrin Derivatives
Ruano, Jose L. Garcia,Castro, Ana M. Martin,Rodriguez, Jesus H.
, p. 7235 - 7241 (2007/10/02)
The reactions of chiral β-keto sulfoxides, R1-CO-CHR2-SOTol (R1 = Me, n-Pr, i-Pr, t-Bu, Ph; R2 = H, Me) with Et2AlCN yield the corresponding sulfinyl cyanohydrins with high yields (85-96percent) and de (>96perce
