144708-85-0Relevant academic research and scientific papers
New efficient method of alkoxymethyl etherification of secondary alcohols
Watanabe, Yosuke,Ikemoto, Tetsuya
, p. 5795 - 5797 (2004)
A new efficient method of MOM etherification of secondary alcohols using 2-(chloromethyl)-3,5-dioxahex-1-ene (Okahara's reagent) is reported.
Synergistic Catalysis for the Umpolung Trifluoromethylthiolation of Tertiary Ethers
Xu, Wentao,Ma, Junyang,Yuan, Xiang-Ai,Dai, Jie,Xie, Jin,Zhu, Chengjian
supporting information, p. 10357 - 10361 (2018/08/06)
The first transition-metal-free, site-specific umpolung trifluoromethylthiolation of tertiary alkyl ethers has been developed, achieving the challenging tertiary C(sp3)–SCF3 coupling under redox-neutral conditions. The synergism of organophotocatalyst 4CzIPN and BINOL-based phosphorothiols can site-selectively cleave tertiary sp3 C(sp3)–O ether bonds in complex molecules initiated by a polarity-matching hydrogen-atom-transfer (HAT) event. The incorporation of several competing benzylic and methine C(sp3)?H bonds in alkyl ethers has little influence on the regioselectivity. Selective difluoromethylthiolation of C?O bonds has also been achieved. This represents not only an important step forward in trifluoromethylthiolation but also a promising means for site-selective C?O bond functionalization of unsymmetrical tertiary alkyl ethers.
Method for preparing tertiary alkyl trifluoromethyl sulfide
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Paragraph 0027-0030, (2018/10/19)
The invention discloses a method for preparing tertiary alkyl trifluoromethyl sulfide. The method includes: using tertiary alkoxy ether as a raw material; under illumination of blue light, in a solution, in an argon atmosphere and at the presence of a small amount of potassium carbonate, reacting with 2-((trifluoromethyl)thio) isoindoline-1, 3-diketone at room temperature through synergistic catalysis of a photocatalyst 4CzIPN and an organic thiol catalyst 4-thionaphthol[2, 1-d:1', 2'-f][1, 3, 2]dioxocycloheptene-4-oxide, wherein the photocatalyst 4CzIPN and the organic thiol catalyst have following structures.
Metal hydrogen sulfates catalyzed methoxymethylation of alcohols under solvent-free conditions
Niknam, Khodabakhsh,Zolfigol, Mohammad Ali,Shayegh, Mohsen,Zare, Reza
, p. 1067 - 1073 (2008/02/13)
Methoxymethylation of a variety of alcohols was performed by using formaldehyde dimethoxy acetal in the presence of metal hydrogen sulfate M(HSO4)n at room temperature and solvent-free conditions. The methoxymethyl ethers (MOM-ethers
HYDROXY-PROTECTING REAGENT AND METHOD OF PROTECTING HYDROXY WITH THE SAME
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Page/Page column 10-11, (2008/06/13)
The present invention relates to a method of protecting a hydroxyl group, which includes reacting a hydroxyl group-containing compound with a compound represented by the formula (I) : wherein R is a phenyl group optionally having substituent(s), an alkyl
Molybdatophosphoric acid as a catalyst for the methoxymethylation of alcohols under solvent-free conditions
Zolfigol, Mohammad Ali,Shiri, Morteza
, p. 165 - 166 (2007/10/03)
The methoxymethylation of alcohols was performed using formaldehyde dimethoxy acetal in the presence of H3PMo12O 40·xH2O at room temperature under solvent-free conditions.
