1447159-43-4Relevant academic research and scientific papers
Creation of molecular complexities via a new Cu-catalyzed cascade reaction: A direct access to novel 2,2′-spirobiindole derivatives
Prasad, Bagineni,Adepu, Raju,Sharma, Atul Kumar,Pal, Manojit
, p. 1259 - 1262 (2015/02/05)
A Cu-mediated unprecedented cascade reaction in the presence of air afforded a conceptually new synthesis of 2,2′-spirobiindole derivatives. This reaction proceeds via the rearrangement of several bonds in a cyclopenta[b]indole framework including a facial selective intramolecular ring closure. The potential of this method is highlighted in the straightforward and single step synthesis of a paullone like compound. This journal is
A Pd-based regioselective strategy to indole-1,2-fused 8- and 9-membered rings: Their evaluation as potential scaffolds for apoptosis in zebrafish
Prasad, Bagineni,Sreenivas, B. Yogi,Sushma, Araka,Yellanki, Swapna,Medisetti, Raghavender,Kulkarni, Pushkar,Pal, Manojit
supporting information, p. 2864 - 2868 (2014/05/06)
A strategy based on Pd-mediated ring closure of 1,2-disubstituted indoles containing an unactivated olefin leading to indole-1,2-fused 8- and 9-membered rings has been developed for the identification of new and potential scaffolds for apoptosis. A large number of fused indole derivatives containing an endocyclic double bond were synthesized using this robust methodology. A representative compound showed promising apoptotic properties in zebrafish embryos. This journal is the Partner Organisations 2014.
Pd-mediated construction of a cyclopentane ring fused with indoles
Prasad, Bagineni,Sreenivas, B. Yogi,Krishna, G. Rama,Kapavarapu, Ravikumar,Pal, Manojit
, p. 6716 - 6718 (2013/07/26)
Unprecedented synthesis of functionalized indoles of potential pharmacological interest has been developed via a Pd-mediated cascade reaction involving an intramolecular Heck coupling followed by the construction of a fused cyclopentane ring in a single pot.
